Cancer Research
[Abstract]
Objective To determine whether the mast cell?MC? subpopulations and tumor-associated macrophages ?TAMs? count has any correlations with clinical outcome in colorectal cancer.Methods The MCs and TAMs count were determined immunohistochemically in 60 patients with colorectal cancer , and investigate the relationship of the number of MCs and TAMs with depth of invasion?lymph node metastasis rate? distant metastasis rates and survival rates.Results ? Both patients with a low MC count and patients with a low TAM count had significantly deeper depth of invasion than those with a high MC count and those with a high TAM count ?pTC. ? The 5 year survival rate estimated was significantly lower in both patients with a low MC count and patients with a low TAM count than in those with a high MC count and those with a high TAM count ?P
Title: Prognostic Significance of Mast Cell Subpopulations and Macrophage in Colorectal Cancer
Category: Cancer Cell
Filename: Prognostic Significance of Mast Cell Subpopulations and Macrophage in Colorectal Cancer.pdf
Pages: 152
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